Application for food and human health

  • Lactic acid bacteria with the ability to modulate the secretion of adipoquines to treat and / or prevent diet-induced obesity.
  • Lactic acid bacteria with esterase activity as probiotics against metabolic syndrome.
  • Bioenriched foods with hydroxycinnamic acids by lactic acid bacteria with cinnamyl ester activity.
  • Lactic acid bacteria and bifidobacteria producing conjugated bioactive lipids in fermented foods.
  • Effect of the administration of lactic acid bacteria and probiotic bifidobacteria in the modification of host lipidoma.
  • Lactic acid bacteria as a processing strategy for the removal of anti-nutritional factors and the generation of bioactive compounds in legumes.
  • Lactic acid bacteria with β-galactosidase activity for probiotic purposes and / or generation of prebiotic galactooligosaccharides from whey.
  • Lactic acid bacteria for the development of flavor compounds in dairy products of goat and sheep origin.

Application to nutrition and animal health

  • Functional foods for the poultry industry: action against salmonellosis and campylobacteriosis.
  • Contribution of bacteria isolated from cereals and seeds to protein digestion in BB chicks.
  • Study of the genus Bifidobacterium in the intestinal tract of poultry. Probiotic potential and effects on avian nutrition.
  • Lactic acid bacteria and related microorganisms as protectors of intestinal digestive function. Its impact on the nutrition of hatchery birds
  • Micro and nanotechnologies of application in the intensive breeding of birds.
  • Study of the structures responsible for the functional and technological properties of probiotic microorganisms for application in poultry farming.
  • Production and conservation of probiotic crops and products for poultry, preserving cellular structures responsible for their functionality.
  • Lactic bacteria with feruloyllesterase activity as third generation inoculants in silages for ruminants.
  • Intracellular signaling-interaction between eukaryotic and prokaryotic cells.


  • Probiotics, pharmabiotics and phytobiotics in the urogenital tract.
  • Probiotic formulations in the prevention of veterinary infections.
  • Cattle (metritis, neonatal diarrhea in calves and steers in intensive fattening systems) Mastitis (cooperation with National University of Rio Cuarto).
  • Probiotics as biological control agents in ranching (collaboration with INSIBIO) and freshwater aquaculture (collaboration with Northeastern National University).


  • Antimicrobial peptides - Bacteriocins: studies of in vivo functionality and molecular characterization of synthetic operons.
  • Genome analysis of lactic acid bacteria from the CERELA collection.
  • Production of group B vitamins (folate, riboflavin, cobalamin (B12), thiamin) by LAB (collaboration with the Technology and Development Laboratory).
  • Yeasts as biocontrol agents.
  • Characterization of antibiotic resistance in bacteria of clinical and / or biotechnological importance.


  • Study of immunobiotic lactic acid bacteria and their cell fractions as an alternative for the development of immunomodulatory products intended for the prevention of respiratory infections in immunocompromised hosts.
  • Immunobiotic lactic acid bacteria in the prevention of bacterial and viral respiratory infections. Study of its mechanisms of action using cutting-edge molecular tools and genomic studies.
  • Identification of recognition patterns and signaling pathways involved in the prevention of respiratory superinfections using immuno-modulatory fractions of lactic acid bacteria.
  • Immunobiotic lactic acid bacteria in the recovery of hematopoiesis in immunosuppressed hosts due to malnutrition or chemotherapy.
  • Impact of immunopotentiating lactic acid bacteria in the immuno-myelopoietic response during infectious / inflammatory processes in immuno-compromised hosts.
  • Expression of antigenic proteins of respiratory pathogens in recombinant lactic bacteria for their potential use as vectors of vaccines.
  • Study of immuno-modulatory molecules of immuno-biotic lactic acid bacteria for their use as adjuvants in the development of mucous vaccines.
  • Effect of immunobiolactic acid bacteria on the interrelation inflammation-hemostasis and its impact on resistance to bacterial and viral respiratory infections.
  • Study of commensal bacteria of the respiratory tract as new generation immuno-biotics to improve respiratory health.
  • Immuno-modulatory capacity of lactic acid bacteria on intra-hepatic innate immunity in inflammatory diseases of the liver.


  • Effect of lactic acid bacteria on the modulation of the intestinal mucosal immune response.
  • Mechanism of action of probiotic lactic bacteria and / or their bacterial fractions and fermented products on the intestinal mucosal immune system in normal situations and in the presence of inflammatory pathologies.
  • Biological mechanisms involved in immune activity mediated by fermented milks with probiotic bacteria and non-bacterial fractions. Studies in models of breast cancer, colon cancer, intestinal inflammation and enteric infections.
  • Effect of lactic bacteria with immunomodulatory and / or anti-oxidant capacities in models of neurodegenerative pathologies.
  • Study of the maturation of the immune system due to the effect of the intestinal microbiota.
  • Implication of non-pathogenic bacteria in the activation / regulation of the intestinal immune system.


  • Control of spoilage organisms in raw materials and processed foods using lactic acid bacteria and/or their metabolites as biopreservatives. Impact on the life of and in industrial losses.
  • BAL-E coli Enterohemorrhagic interaction studies and its contribution to strategies of bioprotection in meat and meat environments.
  • Lactic starters in vegetable fermented products. Application in soy functional foods and other processed products. Metabolites of interest in foods.
  • Use of Lactic Bacteria in natural cosmeceuticals.
  • Bio-conservation of Silos.
  • Proteolytic system of Lactic Acid Bacteria and its role in the production of bioactive peptides.
  • Characterization of transcriptional regulators of lactobacilli.
  • Lactic acid bacteria (native and genetically modified) producing compounds bioactive. Production of group B vitamins (riboflavin, folate and thiamin), enzymes digestive enzymes, anti-inflammatory cytokines and anti-cancer compounds.
  • Evaluation in vitro and in vivo models of deficiencies, intestinal pathologies (colitis, mucositis, colon cancer), breast cancer and neurodegenerative diseases Parkinson's disease.
  • Mannitol Production by Lactic Acid Bacteria.
  • Biotransformation of Selenium by Lactic Bacteria.
  • Fermented drinks based on fruit juice.
  • Lactic cultures of Andean grains (pseudocereals) producing enzymes, functional biomolecules and food ingredients to improve the nutritional properties tional, functional and quality of fermented foods.
  • Bacteriocins as a barrier in biofilm formation by Listeria monocytogenes on industrial surfaces. Use of lactocin AL705. Anti quorum-sensing activity. Is your-proteomic and transcriptomic studies.
  • Probiotics for meat animals in replacement of antibiotics.
  • Identification and characterization of probiotic bacteria from bovine feces in feedlot and pigs. Effect on the structure of the fecal microbiota. Field evaluation (daily weight gain, productivity).
  • Starter cultures for fermented meat products.
  • Synthesis of prebiotic oligosaccharides by lactic bacteria and propionibacteria.
  • Nutritional and functional improvement of legume flour through lactic fermentation.